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  • SOD B®

    SOD B ® is a dried melon juice concentrate naturally rich in SuperOxide Dismutase (SOD), obtained from a non-GMO proprietary variety of Cantaloup melon. SOD B ® is the unique source of bioactive melon SOD worldwide. SOD represents 85 to 90% of the total antioxidant capacity of SOD B ®. As a concentrate, SOD B ® is not pure SOD and also contains secondary antioxidants such as glutathione ...

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  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-6-25u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.

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  • Further Characterization of Bovine Superoxide Dismutase ...

    Further Characterization of Bovine Superoxide Dismutase and Its Isolation from Bovine Heart.pdf Available via license: CC BY 4.0 Content may be subject to copyright.

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  • Superoxide Dismutases, SOD1 and SOD2, Play a Distinct

    2015-2-25u2002·u2002One way that aerobic biological systems counteract the generation of reactive oxygen species (ROS) is with superoxide dismutase proteins SOD1 and SOD2 that metabolize superoxide radicals to molecular oxygen and hydrogen peroxide or scavenge oxygen radicals produced by the extensive oxidation-reduction and electron-transport reactions that occur in mitochondria.

    Get Price
  • Superoxide Dismutase and Glutathione Peroxidase

    2019-10-12u2002·u2002sent study was to measure the activity of the enzymes superoxide dismutase (SOD; Enzyme Commission number [EC] 1.15.1.1) and glutathione peroxidase (SeGSHPx; EC 1.11.1.9) in human milk, to record changes in enzyme activity over time and to determine whether there are differences in activity between the milk of mothers of full-term (FT) and premature (PT) infants. Methods Nine samples were ...

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  • (PDF) Industrial Production of Superoxide Dismutase (SOD ...

    Industrial Production of Superoxide Dismutase (SOD): A Mini Review. Rajesh Kanna Gopal 1 and Sanniyasi Elumalai 2*. 1 Department of Plant Biology and Plant Biotechnology, Presidency College ...

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  • Treatment with a Catalytic Superoxide Dismutase (SOD ...

    The manganese porphyrin superoxide dismutase (SOD) mimetic, manganese (III) meso-tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnP) is a first-in-class oxidoreductase that not only scavenges reactive oxygen species (ROS), like superoxide, but also possesses anti-inflammatory properties and has been proven clinically safe .

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  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities of higher than 1000 units per ...

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  • Association among extracellular superoxide dismutase ...

    2021-4-20u2002·u2002Superoxide dismutase 3 (SOD3), an antioxidant enzyme, is known as extracellular SOD (EC-SOD) because it is the predominant form in extracellular fluids. The diversity of plasma EC-SOD ...

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  • Association among extracellular superoxide dismutase ...

    2021-4-20u2002·u2002Superoxide dismutase 3 (SOD3), an antioxidant enzyme, is known as extracellular SOD (EC-SOD) because it is the predominant form in extracellular fluids. The diversity of plasma EC-SOD ...

    Get Price
  • Dual gene therapy with extracellular superoxide dismutase ...

    2007-1-5u2002·u2002ROS scavengers include catalase and superoxide dismutase (SOD). SOD dismutes superoxide to hydrogen peroxide (H 2 O 2) and catalase detoxifies the H 2 O 2 to H 2 O and O 2. In a prior study, we targeted a single ROS, hydrogen peroxide, for detoxification by catalase gene inoculationn . It reduced demyelination of the optic nerve by 38%.

    Get Price
  • Measurement of superoxide dismutase, catalase and ...

    2009-12-17u2002·u2002General protocols are described to measure the antioxidant enzyme activity of superoxide dismutase (SOD), catalase and glutathione peroxidase. ... with low SOD activity, 5, 10, 25, 50, 100, 200 ...

    Get Price
  • Superoxide Dismutases, SOD1 and SOD2, Play a Distinct

    2015-2-25u2002·u2002One way that aerobic biological systems counteract the generation of reactive oxygen species (ROS) is with superoxide dismutase proteins SOD1 and SOD2 that metabolize superoxide radicals to molecular oxygen and hydrogen peroxide or scavenge oxygen radicals produced by the extensive oxidation-reduction and electron-transport reactions that occur in mitochondria.

    Get Price
  • Therapeutic activity of superoxide dismutase-containing ...

    2017-11-15u2002·u2002Liver ischaemia-reperfusion injury (IRI) may occur during hepatic surgery and is unavoidable in liver transplantation. Superoxide dismutase enzymosomes (SOD-enzymosomes), liposomes where SOD is at the liposomal surface expressing enzymatic activity in intact form without the need of liposomal disruption, were developed with the aim of having a better insight into its antioxidant therapeutic ...

    Get Price
  • Superoxide Dismutase Administration, A Potential Therapy ...

    2013-6-21u2002·u2002Oxidative stress, involved in many diseases, is defined as an impaired balance between reactive oxygen species (ROS) production and antioxidant defences. Antioxidant enzymes such as superoxide dismutase (SOD) play a key role in diminishing oxidative stress. Thus, the removal of ROS by exogenous SODs could be an effective preventive strategy against various diseases. The poor bioavailability of ...

    Get Price
  • Targeted Delivery of Superoxide Dismutase by Chemical ...

    2015-8-27u2002·u2002Objective To improve the half-life and tissue targeting of superoxide dismutase (SOD) in suppressing reactive oxygen species (ROS)-mediated injury, SOD was chemically modified with N,N,N-trimethyl chitosan chloride (TMC) to generate TMC-SOD. Methods In this study, the pharmacokinetics of TMC-SOD had been studied. 125I-radiolabeled TMC-SOD conjugate was administered to healthy mice (6- to 8 ...

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  • Copper

    2021-9-16u2002·u2002Superoxide dismutase Two forms of SOD contain copper: (1) copper/zinc SOD is found within most cells of the body, including red blood cells; and (2) extracellular SOD is a copper-containing enzyme found at high levels in the lungs and low levels in plasma (2) .

    Get Price
  • Defective hematopoiesis and hepatic steatosis in mice with ...

    2001-8-15u2002·u2002Several lines of evidence point to an abnormality in the response of Fanconi anemia cells to reactive oxygen species. To investigate the potential pathologic consequences of an in vivo alteration of redox state in mice lacking one of the Fanconi anemia genes, animals were generated having combined deficiencies of the cytosolic Cu/Zn superoxide dismutase (Sod1) and Fanconi anemia ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002Nitric oxide is removed within seconds in vivo by diffusion over 100 microns through tissues to enter red blood cells and react with oxyhemoglobin. The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-).

    Get Price
  • Association among extracellular superoxide dismutase ...

    2021-4-20u2002·u2002Superoxide dismutase 3 (SOD3), an antioxidant enzyme, is known as extracellular SOD (EC-SOD) because it is the predominant form in extracellular fluids. The diversity of plasma EC-SOD ...

    Get Price
  • Dual gene therapy with extracellular superoxide dismutase ...

    2007-1-5u2002·u2002ROS scavengers include catalase and superoxide dismutase (SOD). SOD dismutes superoxide to hydrogen peroxide (H 2 O 2) and catalase detoxifies the H 2 O 2 to H 2 O and O 2. In a prior study, we targeted a single ROS, hydrogen peroxide, for detoxification by catalase gene inoculationn . It reduced demyelination of the optic nerve by 38%.

    Get Price
  • Measurement of superoxide dismutase, catalase and ...

    2009-12-17u2002·u2002General protocols are described to measure the antioxidant enzyme activity of superoxide dismutase (SOD), catalase and glutathione peroxidase. ... with low SOD activity, 5, 10, 25, 50, 100, 200 ...

    Get Price
  • Superoxide Dismutases, SOD1 and SOD2, Play a Distinct

    2015-2-25u2002·u2002One way that aerobic biological systems counteract the generation of reactive oxygen species (ROS) is with superoxide dismutase proteins SOD1 and SOD2 that metabolize superoxide radicals to molecular oxygen and hydrogen peroxide or scavenge oxygen radicals produced by the extensive oxidation-reduction and electron-transport reactions that occur in mitochondria.

    Get Price
  • Therapeutic activity of superoxide dismutase-containing ...

    2017-11-15u2002·u2002Liver ischaemia-reperfusion injury (IRI) may occur during hepatic surgery and is unavoidable in liver transplantation. Superoxide dismutase enzymosomes (SOD-enzymosomes), liposomes where SOD is at the liposomal surface expressing enzymatic activity in intact form without the need of liposomal disruption, were developed with the aim of having a better insight into its antioxidant therapeutic ...

    Get Price
  • Superoxide Dismutase Administration, A Potential Therapy ...

    2013-6-21u2002·u2002Oxidative stress, involved in many diseases, is defined as an impaired balance between reactive oxygen species (ROS) production and antioxidant defences. Antioxidant enzymes such as superoxide dismutase (SOD) play a key role in diminishing oxidative stress. Thus, the removal of ROS by exogenous SODs could be an effective preventive strategy against various diseases. The poor …

    Get Price
  • Targeted Delivery of Superoxide Dismutase by Chemical ...

    2015-8-27u2002·u2002Objective To improve the half-life and tissue targeting of superoxide dismutase (SOD) in suppressing reactive oxygen species (ROS)-mediated injury, SOD was chemically modified with N,N,N-trimethyl chitosan chloride (TMC) to generate TMC-SOD. Methods In this study, the pharmacokinetics of TMC-SOD had been studied. 125I-radiolabeled TMC-SOD conjugate was administered to healthy …

    Get Price
  • Copper

    2021-9-16u2002·u2002Superoxide dismutase Two forms of SOD contain copper: (1) copper/zinc SOD is found within most cells of the body, including red blood cells; and (2) extracellular SOD is a copper-containing enzyme found at high levels in the lungs and low levels in plasma (2) .

    Get Price
  • Defective hematopoiesis and hepatic steatosis in mice with ...

    2001-8-15u2002·u2002Several lines of evidence point to an abnormality in the response of Fanconi anemia cells to reactive oxygen species. To investigate the potential pathologic consequences of an in vivo alteration of redox state in mice lacking one of the Fanconi anemia genes, animals were generated having combined deficiencies of the cytosolic Cu/Zn superoxide dismutase (Sod1) and Fanconi anemia ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002Nitric oxide is removed within seconds in vivo by diffusion over 100 microns through tissues to enter red blood cells and react with oxyhemoglobin. The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-).

    Get Price
  • 20655 - Gene ResultSod1 superoxide dismutase 1, soluble ...

    2021-9-12u2002·u2002superoxide dismutase 1 expression and activity is affected by low dose radiation in a diabetes model Copper-zinc superoxide dismutase deficiency impairs sperm motility and in vivo fertility. Results highlight misfolded SOD1 as common to two Amyotrophic lateral sclerosis (ALS) rodent animal models and familial ALS patient lymphoblasts with four ...

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  • Superoxide Dismutases, SOD1 and SOD2, Play a Distinct Role ...

    2015-2-25u2002·u2002One way that aerobic biological systems counteract the generation of reactive oxygen species (ROS) is with superoxide dismutase proteins SOD1 and SOD2 that metabolize superoxide radicals to molecular oxygen and hydrogen peroxide or scavenge oxygen radicals produced by the extensive oxidation-reduction and electron-transport reactions that occur in mitochondria.

    Get Price
  • Randox Lyophilized reagents - All the products on MedicalExpo

    Superoxide Dismutase (Ransod) Control 'A dedicated Superoxide Dismutase control for use in the routine monitoring of the Randox Ransod assay on clinical chemistry analysers. Features & Benefits Lyophilised for enhanced stability Bovine ...

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  • Lipid peroxides, superoxide dismutase and circulating IL-8 ...

    2005-6-30u2002·u2002The range of the standard curve was 0.1 to 5 μM per milliliter blood serum. Superoxide dismutase activity assay. SOD enzymatic activity was measured as previously described, using reagents from Sigma. SOD from bovine erythrocytes was used in constructing the standard curve, which ranged from 15–750 mU).

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  • Superoxide Dismutase and Glutathione Peroxidase Content of ...

    2019-10-12u2002·u2002sent study was to measure the activity of the enzymes superoxide dismutase (SOD; Enzyme Commission number [EC] 1.15.1.1) and glutathione peroxidase (SeGSHPx; EC 1.11.1.9) in human milk, to record changes in enzyme activity over time and to determine whether there are differences in activity between the milk of mothers of full-term (FT) and premature (PT) infants. …

    Get Price
  • Regulation of Cu-Zn superoxide dismutase on SCN2A in SH ...

    2013-11-11u2002·u2002Cu-Zn superoxide dismutase (Cu-Zn SOD) is a key enzyme in the dismutation of superoxide radicals, which result from the cellular oxidative metabolism process of cells, converting them into hydrogen peroxide . Increasing evidence suggests a role for oxidative stress in the manifestation of epilepsy (14–17).

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  • Reagent, Reagent kit - All medical device manufacturers ...

    for coagulation analysis for blood typing for blood phenotyping for blood gas analysis ESR for platelets. for food safety (55) for food products food intolerance. for colorimetry (48) for turbidimetry (40) for nephelometry. for environmental analysis (39) for water analysis. cardiology (28) for cancers (24) for sperm analysis (22) industrial ...

    Get Price
  • Free Fatty Acids, Lipopolysaccharide and IL-1α Induce ...

    Blood glucose was 392 (317–456) mg/dl in the diabetic and 83 (59–92) mg/dl in control animals (p = 0.029). Seven week old male C57BL/6 mice from Charles River (Sulzfeld, Germany) were kept on a high fat diet (HFD, 7 mice) or standard chow (SD, 7 mice) for 14 weeks.

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  • Low glucose induces mitochondrial reactive oxygen species ...

    2017-4-12u2002·u2002Etomoxir and manganese superoxide dismutase (MnSOD) overexpression ameliorated the endothelial dysfunction induced by low glucose. (a) Representative images of protein expression determined by western blotting in bovine aortic endothelial cells (BAECs) under the indicated conditions for 1 h. eNOS, endothelial nitric oxide synthase; p-eNOS ...

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  • Stem Cells Need Nutrition Too! With Ann Harrison

    2021-2-24u2002·u2002Stem cells are amazing but they need nutrition too. Bob and Ann share some great ways to make sure your Stem cells get what they need to renew and repair your body so you can live your best life. Sit back, relax and get ready to live forever young. I'm here with Ann Harrison, the author of Rev Up Your Stem Cell Power.

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  • Superoxide Dismutase (SOD) Activity Colorimetric Assay

    Superoxide dismutase (SOD) is one of the most important antioxidative enzymes. It catalyzes the dismutation of the superoxide anion into hydrogen peroxide and molecular oxygen. The sensitive SOD assay kit utilizes WST-1 that produces a water-soluble formazan dye upon reduction with superoxide …

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  • Regulation of Cu-Zn superoxide dismutase on SCN2A in

    In order to evaluate SCN2A as a candidate gene for epileptic susceptibility and the use of a Cu-Zn superoxide dismutase (SOD) supplement as a potential therapy for epilepsy, SCN2A expression in the cortex and the correlation between SCN2A and Cu-Zn SOD in SH-SY5Y cells were examined. SCN2A expression and the concentration of Cu-Zn SOD in the cerebral cortexes of patients with primary and ...

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  • Treatment with a Catalytic Superoxide Dismutase (SOD ...

    The manganese porphyrin superoxide dismutase (SOD) mimetic, manganese (III) meso-tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnP) is a first-in-class oxidoreductase that not only scavenges reactive oxygen species (ROS), like superoxide, but also possesses anti-inflammatory properties and has been proven clinically safe .

    Get Price
  • Extracellular Superoxide Dismutase Is a Major Determinant ...

    2003-8-21u2002·u2002The bioavailability of nitric oxide (NO) within the vascular wall is limited by superoxide anions (O 2 ·−).The relevance of extracellular superoxide dismutase (ecSOD) for the detoxification of vascular O 2 ·− is unknown. We determined the involvement of ecSOD in the control of blood pressure and endothelium-dependent responses in angiotensin II–induced hypertension and renovascular ...

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  • Multiple organ pathology, metabolic abnormalities and ...

    2003-11-9u2002·u2002We added superoxide dismutase (200 units ml −1) to samples prepared in parallel to identify the SOD-sensitive rate of acetylated cytochrome c reduction and, hence, the portion attributable to ...

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  • type 2 diabetes superoxide dismutase ????urine

    type 2 diabetes superoxide dismutase Low blood sugar or hypoglycemia is a complication of type 1 and type ... revealed that MNT with diets containing a low amount of carbohydrates and low GI, and with a high content of protein or Mediterranean diet ... (low fat) is not necessarily the long-term solution as many low-fat foods are high in sugar ...

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  • Post-exposure distribution of selenium and aluminum ions ...

    2018-10-3u2002·u2002The study was conducted to determine how aluminum (Al) and selenium (Se) ions alone and in combination affect superoxide dismutase (SOD) activity and to evaluate the distribution of these elements in the blood and the brain of laboratory mice. SOD activity in mouse brain was evaluated after single-time (within 24 h) and repeated (over 14 days) intraperitoneal (IP) injections of SeO32−, Al3 ...

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  • Pharmacokinetics, tissue distribution and excretion of ...

    2013-1-26u2002·u2002Manganese (III) 5, 10, 15, 20-tetrakis [3-(2-(2-methoxy)-ethoxy) ethoxy] phenyl porphyrin chloride, designated HSJ-0017, is a novel superoxide dismutase mimic. It exhibits strong free-radical scavenging activities in vitro and in vivo. The aim of the present study was to investigate the pharmacokinetics, tissue distribution and excretion of HSJ-0017 in Wistar rats following a single ...

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  • Placental superoxide dismutase 3 mediates benefits of ...

    Kusuyama et al. define a novel mechanism for placental transmission of improved metabolic health to offspring. SOD3 is identified as an exercise-induced and vitamin D-regulated placenta-derived protein that improves glucose homeostasis in offspring. SOD3 activates an AMPK/TET signaling axis resulting in epigenetic changes to metabolic genes in offspring liver.

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  • Reagent, Reagent kit - All medical device manufacturers ...

    for coagulation analysis for blood typing for blood phenotyping for blood gas analysis ESR for platelets. for food safety (55) for food products food intolerance. for colorimetry (48) for turbidimetry (40) for nephelometry. for environmental analysis (39) for water analysis. cardiology (28) for cancers (24) for sperm analysis (22) industrial ...

    Get Price
  • Association among extracellular superoxide dismutase ...

    2021-4-20u2002·u2002Superoxide dismutase 3 (SOD3), an antioxidant enzyme, is known as extracellular SOD (EC-SOD) because it is the predominant form in extracellular fluids. The diversity of plasma EC-SOD ...

    Get Price
  • Dual gene therapy with extracellular superoxide dismutase ...

    2007-1-5u2002·u2002ROS scavengers include catalase and superoxide dismutase (SOD). SOD dismutes superoxide to hydrogen peroxide (H 2 O 2) and catalase detoxifies the H 2 O 2 to H 2 O and O 2. In a prior study, we targeted a single ROS, hydrogen peroxide, for detoxification by catalase gene inoculationn . It reduced demyelination of the optic nerve by 38%.

    Get Price
  • Measurement of superoxide dismutase, catalase and ...

    2009-12-17u2002·u2002General protocols are described to measure the antioxidant enzyme activity of superoxide dismutase (SOD), catalase and glutathione peroxidase. ... with low SOD activity, 5, 10, 25, 50, 100, 200 ...

    Get Price
  • Superoxide Dismutases, SOD1 and SOD2, Play a Distinct

    2015-2-25u2002·u2002One way that aerobic biological systems counteract the generation of reactive oxygen species (ROS) is with superoxide dismutase proteins SOD1 and SOD2 that metabolize superoxide radicals to molecular oxygen and hydrogen peroxide or scavenge oxygen radicals produced by the extensive oxidation-reduction and electron-transport reactions that occur in mitochondria.

    Get Price
  • Therapeutic activity of superoxide dismutase-containing ...

    2017-11-15u2002·u2002Liver ischaemia-reperfusion injury (IRI) may occur during hepatic surgery and is unavoidable in liver transplantation. Superoxide dismutase enzymosomes (SOD-enzymosomes), liposomes where SOD is at the liposomal surface expressing enzymatic activity in intact form without the need of liposomal disruption, were developed with the aim of having a better insight into its antioxidant therapeutic ...

    Get Price
  • Superoxide Dismutase Administration, A Potential Therapy ...

    2013-6-21u2002·u2002Oxidative stress, involved in many diseases, is defined as an impaired balance between reactive oxygen species (ROS) production and antioxidant defences. Antioxidant enzymes such as superoxide dismutase (SOD) play a key role in diminishing oxidative stress. Thus, the removal of ROS by exogenous SODs could be an effective preventive strategy against various diseases. The poor …

    Get Price
  • Targeted Delivery of Superoxide Dismutase by Chemical ...

    2015-8-27u2002·u2002Objective To improve the half-life and tissue targeting of superoxide dismutase (SOD) in suppressing reactive oxygen species (ROS)-mediated injury, SOD was chemically modified with N,N,N-trimethyl chitosan chloride (TMC) to generate TMC-SOD. Methods In this study, the pharmacokinetics of TMC-SOD had been studied. 125I-radiolabeled TMC-SOD conjugate was administered to healthy …

    Get Price
  • Copper

    2021-9-16u2002·u2002Superoxide dismutase Two forms of SOD contain copper: (1) copper/zinc SOD is found within most cells of the body, including red blood cells; and (2) extracellular SOD is a copper-containing enzyme found at high levels in the lungs and low levels in plasma (2) .

    Get Price
  • Defective hematopoiesis and hepatic steatosis in mice with ...

    2001-8-15u2002·u2002Several lines of evidence point to an abnormality in the response of Fanconi anemia cells to reactive oxygen species. To investigate the potential pathologic consequences of an in vivo alteration of redox state in mice lacking one of the Fanconi anemia genes, animals were generated having combined deficiencies of the cytosolic Cu/Zn superoxide dismutase (Sod1) and Fanconi anemia ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002Nitric oxide is removed within seconds in vivo by diffusion over 100 microns through tissues to enter red blood cells and react with oxyhemoglobin. The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-).

    Get Price